tert-Butyl 4-hydroxy-4-phenylpiperidine-1-carboxylate
1-Piperidinecarboxylic acid, 4-hydroxy-4-phenyl-, 1,1-dimethylethylester
CAS: 172734-33-7
Molecular Formula: C16H23NO3
tert-Butyl 4-hydroxy-4-phenylpiperidine-1-carboxylate - Names and Identifiers
tert-Butyl 4-hydroxy-4-phenylpiperidine-1-carboxylate - Physico-chemical Properties
| Molecular Formula | C16H23NO3 |
| Molar Mass | 277.36 |
| Storage Condition | Room Temprature |
| Sensitive | Irritant |
| MDL | MFCD09953388 |
tert-Butyl 4-hydroxy-4-phenylpiperidine-1-carboxylate - Introduction
1-Piperidinecarboxylic acid, 4-hydroxy-4-phenyl-, 1,1-dimethylethylester is an organic compound with the following properties:
Appearance: White crystal or crystalline powder
Molecular formula: C, H, H, N, O
Molecular weight: 308.37g/mol
Melting point: 142-144 ° C
Solubility: Soluble in some organic solvents such as ketones, alcohols and ethers, insoluble in water
1-Piperidinecarboxylic acid, 4-hydroxy-4-phenyl-, 1,1-dimethylethylester is commonly used as an intermediate in drug synthesis. It can be obtained by reacting 4-phenyl-4-hydroxypiperidine with a Boc protecting group. Because the active compound can be obtained by reducing the protective group, it plays an important role in the synthesis of drugs.
The method of preparing 1-Piperidinecarboxylic acid, 4-hydroxy-4-phenyl-, 1,1-dimethylethylester is generally reacting 4-phenyl-4-hydroxypiperidine with dimethyl diisopropyl carbonate (Di-tert-butyl dicarbonate), the desired product is obtained after the reaction.
Regarding safety information, the specific hazards of 1-Piperidinecarboxylic acid, 4-hydroxy-4-phenyl-, 1,1-dimethylethylester need to be evaluated in more detail by the official. However, in general, personal protective equipment such as chemical goggles, gloves and laboratory coats should be worn during operation. During operation, direct contact with skin and inhalation of dust should be avoided. During operation, attention should be paid to a well-ventilated laboratory environment to avoid inhalation of gas or steam. If splashed into the eyes or skin, rinse immediately with plenty of water and seek medical help.
Appearance: White crystal or crystalline powder
Molecular formula: C, H, H, N, O
Molecular weight: 308.37g/mol
Melting point: 142-144 ° C
Solubility: Soluble in some organic solvents such as ketones, alcohols and ethers, insoluble in water
1-Piperidinecarboxylic acid, 4-hydroxy-4-phenyl-, 1,1-dimethylethylester is commonly used as an intermediate in drug synthesis. It can be obtained by reacting 4-phenyl-4-hydroxypiperidine with a Boc protecting group. Because the active compound can be obtained by reducing the protective group, it plays an important role in the synthesis of drugs.
The method of preparing 1-Piperidinecarboxylic acid, 4-hydroxy-4-phenyl-, 1,1-dimethylethylester is generally reacting 4-phenyl-4-hydroxypiperidine with dimethyl diisopropyl carbonate (Di-tert-butyl dicarbonate), the desired product is obtained after the reaction.
Regarding safety information, the specific hazards of 1-Piperidinecarboxylic acid, 4-hydroxy-4-phenyl-, 1,1-dimethylethylester need to be evaluated in more detail by the official. However, in general, personal protective equipment such as chemical goggles, gloves and laboratory coats should be worn during operation. During operation, direct contact with skin and inhalation of dust should be avoided. During operation, attention should be paid to a well-ventilated laboratory environment to avoid inhalation of gas or steam. If splashed into the eyes or skin, rinse immediately with plenty of water and seek medical help.
Last Update：2024-04-09 20:45:29
